Alternating Hemiplegia of Childhood in Half-Sisters
- 1 February 2000
- journal article
- case report
- Published by SAGE Publications in Journal of Child Neurology
- Vol. 15 (2), 128-130
- https://doi.org/10.1177/088307380001500212
Abstract
We present the family of two girls affected with alternating hemiplegia of childhood who were born to the same mother and different fathers. Previous reports suggested mitochondrial dysfunction as an etiologic mechanism for this disorder. Muscle biopsy, including a measurement of the respiratory chain enzymes, performed in one of the sisters showed no mitochondrial abnormalities. The mode of inheritance is not certain, but an autosomal-dominant gene is most likely. (J Child Neurol 2000;15:128-130).Keywords
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