Chicken genome: Current status and future opportunities
Open Access
- 8 December 2005
- journal article
- review article
- Published by Cold Spring Harbor Laboratory in Genome Research
- Vol. 15 (12), 1692-1698
- https://doi.org/10.1101/gr.4141805
Abstract
The chicken genome sequence is important for several reasons. First, the chicken shared a common ancestor with mammals ∼310 million years ago (Mya) at a phylogenetic distance not previously covered by other genome sequences. It therefore fills a gap in our knowledge and understanding of the evolution and conservation of genes, regulatory sequences, genomes, and karyotypes. The chicken is also a major source of protein in the world, with billions of birds used in meat and egg production each year. It is the first livestock species to be sequenced and so leads the way for others. The sequence and the 2.8 million genetic polymorphisms defined in a parallel project are expected to benefit agriculture and cast new light on animal domestication. Also, as the first bird to be sequenced, it is a model for the 9600 avian species thought to exist today. Many of the features of the chicken genome and its biology make it an ideal organism for studies in development and evolution, along with applications in agriculture and medicine.Keywords
This publication has 58 references indexed in Scilit:
- Chicken orthologues of mammalian imprinted genes are clustered on macrochromosomes and replicate asynchronouslyTrends in Genetics, 2005
- The avian genome uncoveredTrends in Ecology & Evolution, 2005
- The ChickDevelopmental Cell, 2005
- Sequence and comparative analysis of the chicken genome provide unique perspectives on vertebrate evolutionNature, 2004
- Evolution and functional classification of vertebrate gene desertsGenome Research, 2004
- Structural and functional analysis of a 0.5-Mb chicken region orthologous to the imprinted mammalianAscl2/Mash2–Igf2–H19regionGenome Research, 2004
- Transcriptome analysis for the chicken based on 19,626 finished cDNA sequences and 485,337 expressed sequence tagsGenome Research, 2004
- Comparative Gene Prediction in Human and MouseGenome Research, 2003
- The origin and evolution of model organismsNature Reviews Genetics, 2002
- The ribosomal RNA gene cluster in aneuploid chickens: evidence for increased gene dosage and regulation of gene expression.The Journal of cell biology, 1985