We report three new cases of allergic contact dermatitis due to vitamins in cosmetic creams. The first patient was diagnosed with worsening rosacea but had allergic contact dermatitis from α-tocopherol in a moisturizing cream. The second and third cases presented as acute eyelid dermatitis due to vitamin K in eyelid lifter creams. Repeated open application testing and patch tests with the actual products and individual components of the creams were useful in establishing the diagnosis.