Boronate ester cross-linked PVA hydrogels for the capture and H2O2-mediated release of active fluorophores

Abstract
A new set of PVA hydrogels were formed using the boronate ester fluorescent probe PF1 and the novel boronate fluorescent probe PT1 as the covalent crosslinkers. Treatment with aqueous H2O2 allowed triggered release of the fluorescent dye accompanied by complete dissolution of the hydrogel.
Funding Information
  • Medical Research Council (MR/N0137941/1)
  • National Institutes of Health (1 S10 OD021508, R01 GM103790)
  • Engineering and Physical Sciences Research Council (EP/R003556/1, EP/R003939/1)
  • Public Health England
  • University of Kent
  • Royal Society
  • Welch Foundation (F-0018)