Nonclonal Emergence of Colistin-Resistant Klebsiella pneumoniae Isolates from Blood Samples in South Korea
- 1 January 2010
- journal article
- research article
- Published by American Society for Microbiology in Antimicrobial Agents and Chemotherapy
- Vol. 54 (1), 560-562
- https://doi.org/10.1128/aac.00762-09
Abstract
In vitro activities of colistin and other drugs were tested against 221 Klebsiella pneumoniae isolates that were collected between 2006 and 2007 in nine tertiary care South Korean hospitals from patients with bacteremia. The clonality of colistin-resistant K. pneumoniae (CRKP) isolates was assessed by multilocus sequence typing (MLST). We found that 15 isolates (6.8%) were resistant to colistin. MLST showed that CRKP isolates were nonclonal, with colistin resistance in K. pneumoniae occurring independently and not by clonal spreading.This publication has 16 references indexed in Scilit:
- Colistin Heteroresistance in Acinetobacter and Its Association with Previous Colistin TherapyAntimicrobial Agents and Chemotherapy, 2008
- High rates of resistance to colistin and polymyxin B in subgroups of Acinetobacter baumannii isolates from KoreaJournal of Antimicrobial Chemotherapy, 2007
- Antibiograms of Multidrug-Resistant Clinical Acinetobacter baumannii: Promising Therapeutic Options for Treatment of Infection with Colistin-Resistant StrainsClinical Infectious Diseases, 2007
- Colistin-resistant isolates of Klebsiella pneumoniae emerging in intensive care unit patients: first report of a multiclonal clusterJournal of Antimicrobial Chemotherapy, 2007
- Colistin: the re-emerging antibiotic for multidrug-resistant Gram-negative bacterial infectionsThe Lancet Infectious Diseases, 2006
- The in-vitro activity of colistin in gram-negative bacteria.2006
- Global assessment of the antimicrobial activity of polymyxin B against 54 731 clinical isolates of Gram-negative bacilli: report from the SENTRY antimicrobial surveillance programme (2001–2004)Clinical Microbiology & Infection, 2006
- Multilocus Sequence Typing of Klebsiella pneumoniae Nosocomial IsolatesJournal of Clinical Microbiology, 2005
- Emergence of KPC-Possessing Klebsiella pneumoniae in Brooklyn, New York: Epidemiology and Recommendations for DetectionAntimicrobial Agents and Chemotherapy, 2005
- Carbapenemase-producing Klebsiella pneumoniae in Brooklyn, NY: molecular epidemiology and in vitro activity of polymyxin B and other agentsJournal of Antimicrobial Chemotherapy, 2005