Cerebral physiology
Open Access
- 1 March 2013
- journal article
- research article
- Published by Elsevier BV in Continuing Education in Anaesthesia Critical Care & Pain
- Vol. 13 (4), 113-118
- https://doi.org/10.1093/bjaceaccp/mkt001
Abstract
The brain is a very complex organ which needs a continuous delivery of oxygen and nutrients. To sustain consciousness, satisfactory perfusion and adequate oxygen delivery is vital but it is equally essential to maintain a constant supply of glucose as the brain has virtually no stores of glucose. Loss of consciousness ensues within seconds of ischaemia secondary to a reduction in cerebral blood flow (CBF), with permanent brain damage occurring with 3–8 min of insufficient blood supply.1 The brain also has a unique heterogeneous structure with areas of variable blood supply that is directly related to its function and metabolism.Keywords
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