The Importance of Negative Superhelicity in Inducing the Formation of G-Quadruplex and i-Motif Structures in the c-Myc Promoter: Implications for Drug Targeting and Control of Gene Expression
- 22 April 2009
- journal article
- research article
- Published by American Chemical Society (ACS) in Journal of Medicinal Chemistry
- Vol. 52 (9), 2863-2874
- https://doi.org/10.1021/jm900055s
Abstract
No abstract availableKeywords
This publication has 55 references indexed in Scilit:
- Structures, folding patterns, and functions of intramolecular DNA G-quadruplexes found in eukaryotic promoter regionsBiochimie, 2008
- Intramolecularly folded G-quadruplex and i-motif structures in the proximal promoter of the vascular endothelial growth factor geneNucleic Acids Research, 2008
- The relationship of potential G-quadruplex sequences in cis-upstream regions of the human genome to SP1-binding elementsNucleic Acids Research, 2008
- Trisubstituted Isoalloxazines as a New Class of G-Quadruplex Binding Ligands: Small Molecule Regulation of c-kit Oncogene ExpressionJournal of the American Chemical Society, 2007
- Quartets in G‐majorEMBO Reports, 2007
- Formation of Pseudosymmetrical G-Quadruplex and i-Motif Structures in the Proximal Promoter Region of the RET OncogeneJournal of the American Chemical Society, 2007
- A common topology for bacterial and eukaryotic transcription initiation?EMBO Reports, 2007
- G-quadruplexes in promoters throughout the human genomeNucleic Acids Research, 2006
- The FUSE/FBP/FIR/TFIIH system is a molecular machine programming a pulse of c-myc expressionThe EMBO Journal, 2006
- G-quadruplex formation within the promoter of the KRAS proto-oncogene and its effect on transcriptionNucleic Acids Research, 2006