Representing uncertainty: the role of cost‐effectiveness acceptability curves
Top Cited Papers
- 20 July 2001
- journal article
- research article
- Published by Wiley in Health Economics
- Vol. 10 (8), 779-787
- https://doi.org/10.1002/hec.635
Abstract
Decision‐making in health care is inevitably undertaken in a context of uncertainty concerning the effectiveness and costs of health care interventions and programmes. One method that has been suggested to represent this uncertainty is the cost‐effectiveness acceptability curve. This technique, which directly addresses the decision‐making problem, has advantages over confidence interval estimation for incremental cost‐effectiveness ratios. However, despite these advantages, cost‐effectiveness acceptability curves have yet to be widely adopted within the field of economic evaluation of health care technologies. In this paper we consider the relationship between cost‐effectiveness acceptability curves and decision‐making in health care, suggest the introduction of a new concept more relevant to decision‐making, that of the cost‐effectiveness frontier, and clarify the use of these techniques when considering decisions involving multiple interventions. We hope that as a result we can encourage the greater use of these techniques. Copyright © 2001 John Wiley & Sons, Ltd.Keywords
This publication has 16 references indexed in Scilit:
- Definition, interpretation and calculation of cost-effectiveness acceptability curvesHealth Economics, 2000
- Cost effectiveness of an intensive blood glucose control policy in patients with type 2 diabetes: economic analysis alongside randomised controlled trial (UKPDS 41)BMJ, 2000
- Inference for the cost-effectiveness acceptability curve and cost-effectiveness ratio.PharmacoEconomics, 2000
- A Bayesian approach to stochastic cost-effectiveness analysisHealth Economics, 1999
- Handling uncertainty when performing economic evaluation of healthcare interventions.Health Technology Assessment, 1999
- Confidence intervals or surfaces? Uncertainty on the cost-effectiveness planeHealth Economics, 1998
- Cost effectiveness analysis of improved blood pressure control in hypertensive patients with type 2 diabetes: UKPDS 40BMJ, 1998
- Going beyond the single number: Using probabilistic risk assessment to improve risk managementHuman and Ecological Risk Assessment: An International Journal, 1996
- The Decision Rules of Cost-Effectiveness AnalysisPharmacoEconomics, 1996
- Costs, effects and C/E‐ratios alongside a clinical trialHealth Economics, 1994