Mean Platelet Volume in Recurrent Aphthous Stomatitis and Behçet Disease
- 13 June 2013
- journal article
- Published by SAGE Publications in Angiology
- Vol. 65 (2), 161-165
- https://doi.org/10.1177/0003319713492375
Abstract
Behcet disease (BD) and recurrent aphthous stomatitis (RAS) are systemic inflammatory diseases, but the exact pathogenesis of both the diseases is unknown. Mean platelet volume (MPV) is an indicator of platelet activation. The aim of this study was to investigate the MPV levels in patients with BD, RAS, and healthy participants. A total of 61 patients with BD, 60 patients with RAS, and 60 healthy controls were included in this study. The MPV levels and erythrocyte sedimentation rate in patients with BD and RAS groups were significantly higher than the control groups (P < .001). In the BD group as well as in the RAS group, the disease activity does not affect the levels of MPV. The MPV levels may be used as a cheap and feasible diagnostic marker in patients with BD and RAS. Nevertheless, the MPV does not have a predictive value in differentiating the diagnosis of BD and RAS.Keywords
This publication has 30 references indexed in Scilit:
- Recurrent aphthous stomatitis: a reviewJournal of Oral Pathology & Medicine, 2012
- Platelet soluble CD40L and matrix metalloproteinase 9 activity are proinflammatory mediators in Behçet disease patientsThrombosis and Haemostasis, 2012
- Interleukin‐2, interleukin‐6 and T regulatory cells in peripheral blood of patients with Behçet’s disease and recurrent aphthous ulcerationsJournal of Oral Pathology & Medicine, 2011
- Age, gender and disease-related platelet and neutrophil activation ex vivo in whole blood samples from patients with Behcet's diseaseRheumatology, 2011
- Behcet’s disease: from east to westClinical Rheumatology, 2010
- Might platelet-leucocyte complexes be playing a role in major vascular involvement of Behçet's disease? A comparative studyBlood Coagulation & Fibrinolysis, 2010
- Increased Mean Platelet Volume in Behçet's Disease with Thrombotic TendencyThe Tohoku Journal of Experimental Medicine, 2010
- Mean platelet volume in psoriasis and psoriatic arthritisClinical Rheumatology, 2009
- Inflammatory bowel diseaseInflammatory Bowel Diseases, 2009
- Behçet’s disease and complex aphthosisJournal of the American Academy of Dermatology, 1999