Antitoxins: novel strategies to target agents of bioterrorism
- 1 September 2004
- journal article
- review article
- Published by Springer Science and Business Media LLC in Nature Reviews Microbiology
- Vol. 2 (9), 721-726
- https://doi.org/10.1038/nrmicro977
Abstract
Never before has there been such a strong possibility that biological agents might be used indiscriminately on civilian populations. This review focuses on the use of antitoxins - antibodies, receptor decoys, dominant-negative inhibitors of translocation, small-molecule inhibitors and substrate analogues - to counteract those biological weapons for which toxins are an important mechanism of disease pathogenesis.Keywords
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