Adverse drug reaction reporting in a pharmacovigilance centre of Nepal.
- 31 May 2012
- journal article
- Published by Andrew John Publishing, Inc. in Australasian Medical Journal
- Vol. 5 (5), 268-71
- https://doi.org/10.4066/amj.2012.1142.
Abstract
Pharmacovigilance is the "science and activities relating to the detection, assessment, understanding and prevention of adverse effects or any other drug related problems". Nepal joined the international pharmacovigilance programme as a full member in 2007. KIST Medical College, Lalitpur, Nepal joined the national programme as a regional centre from mid-July 2008. Currently, the pattern and scope of adverse drug reactions (ADRs) in Nepal remains unexplored. To observe and analyse the pattern of ADRs at KIST Medical College, Lalitpur, Nepal. A retrospective analysis of all ADRs reported to the centre from mid July 2008 to July 2011 was performed. Data was analysed for ADR severity, causality, and preventability. A total of 113 ADR reports were obtained from various clinical departments. The maximum number of reactions was due to antimicrobials, followed by anti-hypertensives and NSAIDs. Antimicrobials were the commonest group of drugs causing ADRs and the most commonly seen ADR was maculopapular rash followed by diarrhea and vomiting.This publication has 10 references indexed in Scilit:
- Cutaneous adverse drug reactions: a 9-year study from a South Indian HospitalPharmacoepidemiology and Drug Safety, 2005
- A 6-month prospective survey of cutaneous drug reactions in a hospital settingBritish Journal of Dermatology, 2003
- Adverse drug reactions in a South Indian hospital—their severity and cost involvedPharmacoepidemiology and Drug Safety, 2003
- Comment: hospital admissions resulting from preventable adverse drug reactions.Annals of Pharmacotherapy, 2003
- Self-medication and non-doctor prescription practices in Pokhara valley, Western Nepal: a questionnaire-based studyBMC Family Practice, 2002
- Adverse drug reactions among inpatients in a north Indian referral hospital.2000
- Preventability and severity assessment in reporting adverse drug reactionsAmerican Journal of Health-System Pharmacy, 1992
- Prospective study of cutaneous drug reactions.1989
- Sex-Related Differences in Drug Disposition in ManClinical Pharmacokinetics, 1984
- A method for estimating the probability of adverse drug reactionsClinical Pharmacology & Therapeutics, 1981