Raspberry Ketone from Submerged Cultured Cells of the Basidiomycete Nidula niveo‐tomentosa
- 1 January 2001
- journal article
- Published by Wiley in Biotechnology Progress
- Vol. 17 (3), 568-572
- https://doi.org/10.1021/bp010011b
Abstract
The basidiomycete Nidula niveo-tomentosa produced 4-(4-hydroxyphenyl)-butan-2-one (raspberry ketone), one of the character impact components of raspberry flavor, and its corresponding alcohol. A systematic attempt was made to improve the productivity of this fungus. Variation of nutrient medium composition, precursor amount, time of supplementation, and cultivation period yielded a 50-fold increase in metabolite concentrations. Raspberry ketone and alcohol were easily isolated from the culture medium by solvent extraction. Glycosidically bound forms or accumulation of raspberry compounds in fungal cells were not detected. This microbial process offers an alternative for the production of natural raspberry flavor.Keywords
This publication has 13 references indexed in Scilit:
- Production and Elicitation of Benzalacetone and the Raspberry Ketone in Cell Suspension Cultures of Rubus idaeusBiotechnology Progress, 2000
- Microbial FlavorsPublished by Springer Science and Business Media LLC ,1999
- Production of Benzaldehyde and Benzyl Alcohol by the Mushroom Polyporus tuberaster K2606Journal of Agricultural and Food Chemistry, 1994
- Glycosidically Bound Norisoprenoids from Vitis vinifera cv. Riesling LeavesJournal of Agricultural and Food Chemistry, 1994
- Production of flavours by microorganismsProcess Biochemistry, 1992
- (p-Hydroxyphenyl)butan-2-one levels in raspberries determined by chromatographic and organoleptic methodsJournal of Agricultural and Food Chemistry, 1992
- Monoaryl and cyclohexenone glycosides from needles of Pinus sylvestrisPhytochemistry, 1988
- Phenolic metabolites of the bird's nest fungus Nidula niveo-tomentosaPhytochemistry, 1980
- Some New Three Level Designs for the Study of Quantitative VariablesTechnometrics, 1960
- Über die Guttation bei PilzenPlanta, 1959