Effect of treatment of hyperlipidaemia on haemostatic variables.
- 11 October 1980
- Vol. 281 (6246), 973-974
- https://doi.org/10.1136/bmj.281.6246.973
Abstract
The haemostatic function of 11 men with hyperlipidaemia was measured before and after they were treated with a carbohydrate-reduced, fat-modified diet. After treatment, which significantly reduced serum triglyceride and cholesterol concentrations, they showed a significant fall in mean levels of clotting factors VII, VIII, and X and a rise in fibrinolytic activity. These findings suggest that haemostatic function may be important in the pathogenesis of ischaemic heart disease.Keywords
This publication has 12 references indexed in Scilit:
- HÆMOSTATIC FUNCTION AND CARDIOVASCULAR DEATH: EARLY RESULTS OF A PROSPECTIVE STUDYThe Lancet, 1980
- EFFECT OF TREATMENT OF HYPERTRIGLYCERIDÆMIA ON HIGH AND LOW DENSITY LIPOPROTEIN CHOLESTEROL CONCENTRATIONSThe Lancet, 1979
- Risk factors for myocardial infarction in the Stockholm prospective study. A 14-year follow-up focussing on the role of plasma triglycerides and cholesterol.1979
- Association of serum lipids and obesity with cardiovascular mortality.BMJ, 1977
- POPULATION-BASED DISTRIBUTIONS OF HAEMOSTATIC VARIABLESBritish Medical Bulletin, 1977
- An Epidemiological Study of the Haemostatic and Other Effects of Oral ContraceptivesBritish Journal of Haematology, 1976
- Experience with Simplified Scheme of Treatment of HyperlipidaemiaBMJ, 1974
- The effect of combined treatment with phenformin and stanazolol on blood lipids and fibrinolytic activity in patients with hypertriglyceridaemiaAtherosclerosis, 1974
- Multivariate Analysis of Risk Factors for Coronary Heart DiseaseCirculation, 1973
- Serum Cholesterol, Lipoproteins, and the Risk of Coronary Heart DiseaseAnnals of Internal Medicine, 1971