Fracture Risk in Patients Treated for Hyperthyroidism
- 1 April 2000
- journal article
- research article
- Published by Mary Ann Liebert Inc in Thyroid®
- Vol. 10 (4), 341-348
- https://doi.org/10.1089/thy.2000.10.341
Abstract
AimTo study fracture risk and risk factors for fractures in patients with hyperthyroidism. DesignHistorical follow-up. Material and MethodsA total of 864 patients with diffuse toxic goiter (ICD 10: E05.0) or toxic nodular goiter (E05.2) were contacted through a self-administered questionnaire. Each respondent was compared to an age: (±5 years) and gender-matched control from a random sample of the background population who responded to the same questionnaire. ResultsAmong the patients 621 (72%) responded and of these 617 could be analyzed. Within the first 5 years before the diagnosis, the patients had the same fracture risk as the controls (RR = 1.2, 95% CI; 0.7-2.0). After the diagnosis, fracture risk was elevated among the patients (RR = 1.7, 95% CI: 1.2-2.3), especially in the age group 50 years or older (RR = 2.2, 95% CI: 1.5-3.3). Fracture risk was elevated for fractures of the spine (RR = 8.9, 95% CI: 1.6-48.4), and the forearms (RR = 3.1, 95% CI: 1.6-6.2), but not at other skeletal sites. Treatmen...Keywords
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