Navigating the road ahead: addressing challenges for use of metabolomics in epidemiology studies
- 12 February 2014
- journal article
- editorial
- Published by Springer Science and Business Media LLC in Metabolomics
- Vol. 10 (2), 176-178
- https://doi.org/10.1007/s11306-014-0636-z
Abstract
Metabolomics platforms allow for the measurement of hundreds to thousands of unique small chemical entities, as well as offer extensive coverage of metabolic markers related to obesity, diet, smoking, and other exposures of high interest to health scientists. Nevertheless, its potential use as a tool in population-based study design has not been fully explored. As the field of metabolomics continues to mature, and in part, accelerate through the National Institutes of Health (NIH) investment of ≤65 million in the Common Fund's Metabolomics Program (https://common fund.nih.gov/metabolomics/index), it is time to consider those challenges most pertinent to epidemiologic studies.This publication has 7 references indexed in Scilit:
- The role of reporting standards for metabolite annotation and identification in metabolomic studiesGigaScience, 2013
- Metabolomics in Epidemiology: Sources of Variability in Metabolite Measurements and ImplicationsCancer Epidemiology, Biomarkers & Prevention, 2013
- Multiplicities in Cancer Research: Ubiquitous and Necessary EvilsJNCI Journal of the National Cancer Institute, 2012
- Cancer Biomarkers: Can We Turn Recent Failures into Success?JNCI Journal of the National Cancer Institute, 2010
- Statistical strategies for avoiding false discoveries in metabolomics and related experimentsMetabolomics, 2006
- Menopausal Estrogen and Estrogen-Progestin Replacement Therapy and Breast Cancer RiskJAMA, 2000
- Nested Case-Control StudiesPreventive Medicine, 1994