Evidence for Different ABC-Transporters in Caco-2 Cells Modulating Drug Uptake
- 1 January 1999
- journal article
- Published by Springer Science and Business Media LLC in Pharmaceutical Research
- Vol. 16 (3), 402-407
- https://doi.org/10.1023/a:1018825819249
Abstract
Purpose. Secretory systems contribute to drug absorption in the gastrointestinal tract. The purpose of this study was the identification of members of the ATP binding cassette superfamily of...Keywords
This publication has 28 references indexed in Scilit:
- P-Glycoprotein (P-gp) Mediated Efflux in Caco-2 Cell Monolayers: The Influence of Culturing Conditions and Drug Exposure on P-gp Expression LevelsJournal of Pharmaceutical Sciences, 1998
- Mechanisms of hepatic transport of cyclosporin A: an explanation for its cholestatic action?1997
- Molecular aspects of hepatobiliary transport.American Journal of Physiology-Gastrointestinal and Liver Physiology, 1997
- Tissue distribution of the multidrug resistance protein.1996
- Age-dependent Expression of P-Glycoprotein gp17O in Caco-2 Cell MonolayersPharmaceutical Research, 1996
- Evidence for a Polarized Efflux System in Caco-2 Cells Capable of Modulating Cyclosporine A TransportBiochemical and Biophysical Research Communications, 1993
- BIOCHEMISTRY OF MULTIDRUG RESISTANCE MEDIATED BY THE MULTIDRUG TRANSPORTERAnnual Review of Biochemistry, 1993
- Epithelial Transport Of Drugs In Cell Culture. I: A Model For Studying The Passive Diffusion Of Drugs Over Intestinal Absorbtive (Caco-2) CellsJournal of Pharmaceutical Sciences, 1990
- Caco-2 Cell Monolayers as a Model for Drug Transport Across the Intestinal MucosaPharmaceutical Research, 1990
- Antigens associated with multidrug resistance in H69AR, a small cell lung cancer cell line.1989