Synthesis of a β-(1→3)-d-Rhamnotetraose by a One-Pot, Multiple Radical Fragmentation
Open Access
- 17 August 2006
- journal article
- letter
- Published by American Chemical Society (ACS) in Organic Letters
- Vol. 8 (19), 4327-4330
- https://doi.org/10.1021/ol061706m
Abstract
A naturally occurring β-(1→3)-d-rhamnotetraose has been constructed under conditions of sequential β-selective mannosylation controlled by the 4,6-O-[1-cyano-2-(2-iodophenyl)-ethylidene] protecting group. The route is concise, proceeding through a late-stage radical deoxygenation that successfully uncovers all four deoxy subunits at once.Keywords
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