The Development of Lung Disease in Cystic Fibrosis Pigs
- 28 April 2010
- journal article
- perspective
- Published by American Association for the Advancement of Science (AAAS) in Science Translational Medicine
- Vol. 2 (29), 29ps20
- https://doi.org/10.1126/scitranslmed.3001130
Abstract
A new study finds that cystic fibrosis pigs develop key features of the often-lethal lung disease seen in cystic fibrosis patients.Keywords
This publication has 28 references indexed in Scilit:
- Cystic Fibrosis Pigs Develop Lung Disease and Exhibit Defective Bacterial Eradication at BirthScience Translational Medicine, 2010
- Pathology of Gastrointestinal Organs in a Porcine Model of Cystic FibrosisThe American Journal of Pathology, 2010
- Normal mouse intestinal mucus release requires cystic fibrosis transmembrane regulator–dependent bicarbonate secretionJCI Insight, 2009
- Disruption of the CFTR Gene Produces a Model of Cystic Fibrosis in Newborn PigsScience, 2008
- The porcine lung as a potential model for cystic fibrosisAmerican Journal of Physiology-Lung Cellular and Molecular Physiology, 2008
- Production of CFTR-null and CFTR-ΔF508 heterozygous pigs by adeno-associated virus–mediated gene targeting and somatic cell nuclear transferJCI Insight, 2008
- Adeno-associated virus–targeted disruption of the CFTR gene in cloned ferretsJCI Insight, 2008
- Cystic FibrosisThe New England Journal of Medicine, 2005
- Defective fluid transport by cystic fibrosis airway epithelia.JCI Insight, 1994
- Increased Bioelectric Potential Difference across Respiratory Epithelia in Cystic FibrosisThe New England Journal of Medicine, 1981