Albendazole treatment of pulmonary hydatid cysts in naturally infected sheep: a study with relevance to the treatment of hydatid cysts in man.
Open Access
- 1 June 1985
- Vol. 40 (6), 453-458
- https://doi.org/10.1136/thx.40.6.453
Abstract
Albendazole was given orally to sheep with naturally occurring live pulmonary and hepatic cysts. The viability of pulmonary cysts was established before treatment by thoracotomy and needle puncture. Both 10 and 20 mg/kg/day doses were found effective in that no viable protoscoleces were found after six weeks' treatment in either group while untreated controls still had viable cysts. In addition, treated animals showed macroscopic and electron microscopic changes. Bone marrow toxicity probably occurred in two sheep.This publication has 19 references indexed in Scilit:
- Albendazole in hydatid disease.BMJ, 1983
- Serum and cyst concentrations of mebendazole and flubendazole in hydatid disease.BMJ, 1982
- Echinococcus granulosus: The influence of mebendazole therapy on the ultrastructural morphology of the germinal layer of hydatid cysts in humans and miceZeitschrift für Parasitenkunde, 1982
- LONG-TERM HIGH-DOSE MEBENDAZOLE FOR CYSTIC HYDATID DISEASE OF LIVER: FAILURE IN TWO CASESAnz Journal of Surgery, 1981
- Immediate and long-term results of surgical treatment of intrathoracic hydatid cysts.1980
- Is Alveolar Hydatid Disease of the Liver Incurable?Annals of Surgery, 1980
- Effect of mebendazole againstEchinococcus granulosus andTaenia hydatigena cysts in naturally infected sheep and relevance to larval tapeworm infections in manZeitschrift für Parasitenkunde, 1980
- PHARMACOKINETICS OF ALBENDAZOLE IN SHEEP1980
- Treatment of hepatic hydatid disease with mebedazole: preliminary results in four cases.BMJ, 1977
- MEBENDAZOLE AND HYDATID CYSTSThe Lancet, 1974