DNA as a Versatile Chemical Component for Catalysis, Encoding, and Stereocontrol
- 28 July 2010
- journal article
- review article
- Published by Wiley in Angewandte Chemie-International Edition
- Vol. 49 (40), 7180-7201
- https://doi.org/10.1002/anie.200906345
Abstract
DNA (deoxyribonucleic acid) is the genetic material common to all of Earth’s organisms. Our biological understanding of DNA is extensive and well‐exploited. In recent years, chemists have begun to develop DNA for nonbiological applications in catalysis, encoding, and stereochemical control. This Review summarizes key advances in these three exciting research areas, each of which takes advantage of a different subset of DNA’s useful chemical properties.Keywords
This publication has 261 references indexed in Scilit:
- Use of Deoxyribozymes in RNA ResearchMethods in Enzymology, 2009
- A Deoxyribozyme, Sero1C, Uses Light and Serotonin to Repair Diverse Pyrimidine Dimers in DNAJournal of Molecular Biology, 2009
- Recent Progress Toward the Templated Synthesis and Directed Evolution of Sequence-Defined Synthetic PolymersCell Chemical Biology, 2009
- The Spliceosome: Design Principles of a Dynamic RNP MachineCell, 2009
- 7‐Azidomethoxy‐Coumarins as Profluorophores for Templated Nucleic Acid DetectionChemBioChem, 2008
- Forty Years of In Vitro EvolutionAngewandte Chemie-International Edition, 2007
- DNA Display III. Solid-Phase Organic Synthesis on Unprotected DNAPLoS Biology, 2004
- DNA Display II. Genetic Manipulation of Combinatorial Chemistry Libraries for Small-Molecule EvolutionPLoS Biology, 2004
- DNA Display I. Sequence-Encoded Routing of DNA PopulationsPLoS Biology, 2004
- Use of intrinsic binding energy for catalysis by a cofactor-independent DNA enzymeJournal of Molecular Biology, 2000