Use of polyunsaturated phosphatidyl choline in HBsAg negative chronic active hepatitis: results of prospective double‐blind controlled trial
- 1 June 1982
- journal article
- clinical trial
- Published by Wiley in Liver International
- Vol. 2 (2), 77-81
- https://doi.org/10.1111/j.1600-0676.1982.tb00182.x
Abstract
— In a prospective double‐blind trial, polyunsaturated phosphatidyl choline therapy (3 g/day) was given in addition to normal maintenance immunosuppressive therapy to 15 patients with HBsAg negative chronic active hepatitis. Histological evidence of disease activity was significantly reduced in the phospholipid‐treated group. The results indicate that polyunsaturated phosphatidyl choline is of value as additional treatment in the management of patients with HBsAg negative chronic active hepatitis whose disease is inadequately controlled with conventional doses of immunosuppressive therapy.This publication has 15 references indexed in Scilit:
- Controlled trial of cyclophosphamide in active chronic hepatitis.BMJ, 1979
- Detection of Antibodies Directed against a Liver-Specific Membrane Lipoprotein in Patients with Acute and Chronic Active HepatitisThe New England Journal of Medicine, 1978
- The morphology of cirrhosis. Recommendations on definition, nomenclature, and classification by a working group sponsored by the World Health Organization.Journal of Clinical Pathology, 1978
- Treatment of Chronic Active HepatitisGastroenterology, 1977
- Controlled trial of synthetic D-penicillamine and prednisone in maintenance therapy for active chronic hepatitis.Gut, 1977
- Effect of essential phospholipids on the properties of ATP-ases of isolated rat liver plasma membranes of young and old animalsMechanisms of Ageing and Development, 1975
- CONTROLLED TRIAL OF PREDNISONE AND AZATHIOPRINE IN ACTIVE CHRONIC HEPATITISThe Lancet, 1973
- Incorporation of Complete Phospholipid Molecules in Cellular Membranes of Rat Liver after Uptake from Blood SerumHoppe-Seyler´s Zeitschrift für physiologische Chemie, 1972
- Controlled Prospective Trial of Corticosteroid Therapy in Active Chronic HepatitisQJM: An International Journal of Medicine, 1971
- LUPOID HEPATITISThe Lancet, 1956