Wernicke's Encephalopathy that Developed during the Introduction Period of Peritoneal Dialysis
Open Access
- 1 January 2013
- journal article
- case report
- Published by Japanese Society of Internal Medicine in Internal Medicine
- Vol. 52 (18), 2093-2097
- https://doi.org/10.2169/internalmedicine.52.9427
Abstract
A 43-year-old man was admitted with end-stage renal disease caused by IgA nephropathy, and was treated with maintenance peritoneal dialysis. The patient developed general fatigue and appetite loss, and his symptoms were gradually aggravated by depression. After approximately 2 months on dialysis, the patient presented with altered consciousness and ophthalmoplegia. Wernicke's encephalopathy was diagnosed based on the presence of classic symptoms and the findings on magnetic resonance imaging. Thiamine replacement therapy was immediately initiated. The patient recovered from most of his neurological symptoms; however, the sequela of Korsakoff syndrome remained. A marginal thiamine deficiency in combination with predisposing factors must be considered when treating dialysis patients.Keywords
This publication has 4 references indexed in Scilit:
- Thiamine-Responsive Acute Neurological Disorders in Nonalcoholic PatientsEuropean Neurology, 2001
- Water‐Soluble Vitamin Levels in Patients Undergoing High‐Flux Hemodialysis and Receiving Long‐Term Oral Postdialysis Vitamin SupplementationArtificial Organs, 2000
- Metabolic Acidosis and Thiamine DeficiencyMayo Clinic Proceedings, 1999
- Underlying Illness in Wernicke’s EncephalopathyEuropean Neurology, 1974