KLF1 drives the expression of fetal hemoglobin in British HPFH
Open Access
- 10 August 2017
- journal article
- Published by American Society of Hematology in Blood
- Vol. 130 (6), 803-807
- https://doi.org/10.1182/blood-2017-02-767400
Abstract
Key Points Introduction of the British HPFH mutation into the fetal globin promoter in a human cell model causes elevated fetal globin expression. The British HPFH mutation creates a de novo binding site both in vitro and in vivo for the potent erythroid activator KLF1.This publication has 27 references indexed in Scilit:
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