Effect of Ruboxistaurin on Blood–Retinal Barrier Permeability in Relation to Severity of Leakage in Diabetic Macular Edema

1 October 2005

journal article
clinical trial
Published by Association for Research in Vision and Ophthalmology (ARVO) in Investigative Ophthalmology & Visual Science

Vol. 46 (10), 3855-3858
https://doi.org/10.1167/iovs.05-0096

Abstract

Purpose. The purpose of the study was to investigate the effect of orally administered ruboxistaurin (RBX, LY333531), a selective protein kinase C β inhibitor, on the permeability of the blood–retinal barrier in patients with diabetic macular edema.

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