Changes in Hospital Mortality Rates in 425 Patients With Acute ST-Elevation Myocardial Infarction and Cardiac Rupture Over a 30-Year Period
- 16 December 2008
- journal article
- research article
- Published by Ovid Technologies (Wolters Kluwer Health) in Circulation
- Vol. 118 (25), 2783-2789
- https://doi.org/10.1161/circulationaha.108.776690
Abstract
Background— Possible changes in the incidence and outcome of cardiac rupture in patients with ST-elevation myocardial infarction over a long period of time have not been investigated. Methods and Results— The incidence of cardiac rupture in ST-elevation myocardial infarction patients and its mortality rate were investigated during a 30-year period divided into 5 intervals (1977 to 1982, 1983 to 1988, 1989 to 1994, 1995 to 2000, and 2001 to 2006). Of a total of 6678 consecutive patients, 425 experienced a free wall rupture (280 with cardiac tamponade: 227 with electromechanical dissociation and 53 with hypotension) or a septal rupture (145). After the exclusion of referrals from other centers (n=44), the incidence of definite cardiac rupture (septal rupture, anatomic evidence of free wall rupture, or electromechanical dissociation) declined progressively (6.2% in 1977 to 1982 to 3.2% in 2001 to 2006; P P P P P P P P P P Conclusion— The decline in the incidence in cardiac rupture and its rate of death over the last 30 years appears to be associated with the increasing use of reperfusion strategies and adjunct medical therapy.This publication has 31 references indexed in Scilit:
- Midterm Clinical and Echocardiographic Results With Patch Glue Repair of Left Ventricular Free Wall RuptureCirculation, 2003
- Outcome and profile of ventricular septal rupture with cardiogenic shock after myocardial infarction: a report from the SHOCK Trial RegistryJournal of the American College of Cardiology, 2000
- Prognosis in rupture of the ventricular septum after acute myocardial infarction and role of early surgical interventionThe American Journal of Cardiology, 1992
- Cardiac rupture, mortality and the timing of thrombolytic therapy: A meta-analysisJournal of the American College of Cardiology, 1990
- Ventricular septal and free wall rupture complicating acute myocardial infarction: Experience in the Multicenter Investigation of Limitation of Infarct SizeAmerican Heart Journal, 1989
- Rupture of the left ventricular free wall during acute myocardial infarction: Analysis of 138 necropsy patients and comparison with 50 necropsy patients with acute myocardial infarction without ruptureThe American Journal of Cardiology, 1988
- Effect of Intravenous Streptokinase on Left Ventricular Function and Early Survival after Acute Myocardial InfarctionThe New England Journal of Medicine, 1987
- Diuretic therapy for mild hypertension: The “real” cost of treatmentThe American Journal of Cardiology, 1984
- Cardiac rupture—challenge in diagnosis and managementThe American Journal of Cardiology, 1977
- Clinical and electrocardiographic features of cardiac rupture following acute myocardial infarctionThe American Journal of Medicine, 1971