PXR, CAR and HNF4α genotypes and their association with pharmacokinetics and pharmacodynamics of docetaxel and doxorubicin in Asian patients
- 18 September 2007
- journal article
- research article
- Published by Springer Science and Business Media LLC in The Pharmacogenomics Journal
- Vol. 8 (2), 139-146
- https://doi.org/10.1038/sj.tpj.6500478
Abstract
No abstract availableKeywords
This publication has 34 references indexed in Scilit:
- Pharmacogenetic Screening of CYP3A and ABCB1 in Relation to Population Pharmacokinetics of DocetaxelClinical Cancer Research, 2006
- Quantification of docetaxel and its main metabolites in human plasma by liquid chromatography/tandem mass spectrometryRapid Communications in Mass Spectrometry, 2005
- Role of Orphan Nuclear Receptors in the Regulation of Drug-Metabolising EnzymesClinical Pharmacokinetics, 2003
- Regulation ofCYP3AGene Transcription by the Pregnane X ReceptorAnnual Review of Pharmacology and Toxicology, 2002
- Eleven Novel Single Nucleotide Polymorphisms in the NRH2 (PXR) Gene, Pour of which Induce Non-synonymous Amino Acid AlterationsDrug Metabolism and Pharmacokinetics, 2002
- Maturity-Onset Diabetes of the Young Type 1 (MODY1)-Associated Mutations R154X and E276Q in Hepatocyte Nuclear Factor 4 (HNF4 ) Gene Impair Recruitment of p300, a Key Transcriptional CoactivatorMolecular Endocrinology, 2001
- The activation function-1 of hepatocyte nuclear factor-4 is an acidic activator that mediates interactions through bulky hydrophobic residuesBiochemical Journal, 2001
- Cytochrome P450 regulation by hepatocyte nuclear factor 4 in human hepatocytes: A study using adenovirus-mediated antisense targetingHepatology, 2001
- Clinical Pharmacokinetics of DocetaxelClinical Pharmacokinetics, 1999
- A Sensitive and Simple High-Performance Liquid Chromatographic Method for the Determination of Doxorubicin and Its Metabolites in PlasmaTherapeutic Drug Monitoring, 1993