Genetic Targeting of the Active Transcription Factor XBP1s to Dendritic Cells Potentiates Vaccine-induced Prophylactic and Therapeutic Antitumor Immunity
Open Access
- 1 February 2012
- journal article
- Published by Elsevier BV in Molecular Therapy
- Vol. 20 (2), 432-442
- https://doi.org/10.1038/mt.2011.183
Abstract
No abstract availableKeywords
This publication has 47 references indexed in Scilit:
- ER stress and its regulator X‐box‐binding protein‐1 enhance polyIC‐induced innate immune response in dendritic cellsEuropean Journal of Immunology, 2011
- TLR activation of the transcription factor XBP1 regulates innate immune responses in macrophagesNature Immunology, 2010
- Transcriptional IL-15-directed in vivo DC targeting DNA vaccineGene Therapy, 2009
- Myeloid-derived suppressor cells as regulators of the immune systemNature Reviews Immunology, 2009
- Endoplasmic reticulum stress and the unfolded protein response are linked to synergistic IFN‐β induction via X‐box binding protein 1European Journal of Immunology, 2008
- A20 is an antigen presentation attenuator, and its inhibition overcomes regulatory T cell–mediated suppressionNature Medicine, 2008
- DNA vaccines: precision tools for activating effective immunity against cancerNature Reviews Cancer, 2008
- The Differentiation and Stress Response Factor XBP-1 Drives Multiple Myeloma PathogenesisCancer Cell, 2007
- Regulatory T cells, tumour immunity and immunotherapyNature Reviews Immunology, 2006
- XBP1 mRNA Is Induced by ATF6 and Spliced by IRE1 in Response to ER Stress to Produce a Highly Active Transcription FactorCell, 2001