Prevalence and Determinant Factors of Sarcopenia in Patients With Type 2 Diabetes
Top Cited Papers
Open Access
- 22 April 2010
- journal article
- Published by American Diabetes Association in Diabetes Care
- Vol. 33 (7), 1497-1499
- https://doi.org/10.2337/dc09-2310
Abstract
OBJECTIVE: We examined prevalence of sarcopenia in Korean patients with type 2 diabetes and compared body compositional parameters between subjects with and without type 2 diabetes. RESEARCH DESIGN AND METHODS: The Korean Sarcopenic Obesity Study (KSOS) included 810 subjects (414 patients with diabetes and 396 control subjects) who were examined using dual-energy X-ray absorptiometry. Prevalence of sarcopenia was defined using the skeletal muscle index (SMI). RESULTS: Prevalence in patients with diabetes and in the control group was 15.7 and 6.9%, respectively. In both men and women, SMI values were significantly decreased in patients with diabetes compared with subjects without diabetes. Furthermore, multiple logistic regression analysis showed that type 2 diabetes was independently associated with sarcopenia. CONCLUSIONS: Type 2 diabetes was associated with increased risk of sarcopenia. These characteristics may contribute to physical disability and metabolic disorders in older adults with diabetes.Keywords
This publication has 12 references indexed in Scilit:
- Excessive Loss of Skeletal Muscle Mass in Older Adults With Type 2 DiabetesDiabetes Care, 2009
- Epidemic obesity and type 2 diabetes in AsiaThe Lancet, 2006
- Decreased Muscle Strength and Quality in Older Adults With Type 2 DiabetesDiabetes, 2006
- A Population-Based Study of Diabetes and Its Characteristics During the Fasting Month of Ramadan in 13 CountriesDiabetes Care, 2004
- Total-body skeletal muscle mass: estimation by a new dual-energy X-ray absorptiometry methodThe American Journal of Clinical Nutrition, 2002
- Low Relative Skeletal Muscle Mass (Sarcopenia) in Older Persons Is Associated with Functional Impairment and Physical DisabilityJournal of the American Geriatrics Society, 2002
- Skeletal muscle mass and distribution in 468 men and women aged 18–88 yrJournal of Applied Physiology, 2000
- Epidemiology of Sarcopenia among the Elderly in New MexicoAmerican Journal of Epidemiology, 1998
- Appendicular skeletal muscle mass: effects of age, gender, and ethnicityJournal of Applied Physiology, 1997
- Appendicular skeletal muscle mass: measurement by dual-photon absorptiometryThe American Journal of Clinical Nutrition, 1990