Supplementary tables 1-7 from PWD/Ph-Encoded Genetic Variants Modulate the Cellular Wnt/β-Catenin Response to Suppress ApcMin-Triggered Intestinal Tumor Formation

Abstract

Supplementary tables 1-7. Supplementary Table 1: GSEA signatures and references (Wnt target genes are taken from the HALLMARK Signature). Supplementary Table 2: 58 differentially expressed genes on chromosome 5, B6 vs C5 APC min normal intestine. Supplementary Table 3: 116 differentially expressed genes not located on chromosome 5, B6 vs C5 APC min normal intestine. Supplementary table 4: Differentially expressed genes on chromosome 5 regulated in cis, trans, or both. Supplementary table 5: Candidate modifier genes differentially expressed between B6 or PWD chromosome 5. Supplementary Table 6: Polymorphisms in human orthologs of mouse genes located on chromosome 5, polymorphic between B6 and PWD, and expressed in the intestine. Supplementary Table 7: PWD polymorphisms on chr5 in genes that are expressed in the intestine and/or in adenoma.