2C or not 2C: defining an improved revascularization grading scale and the need for standardization of angiography outcomes in stroke trials
Top Cited Papers
- 6 February 2013
- journal article
- review article
- Published by BMJ in Journal of NeuroInterventional Surgery
- Vol. 6 (2), 83-86
- https://doi.org/10.1136/neurintsurg-2013-010665
Abstract
However, the definition of ‘successful’ or adequate recanalization/reperfusion as an angiographic endpoint for treatment effect in such trials has become increasingly varied and confusing. The different grading scales and non-standardized definitions of successful thrombectomy reported in published stroke trials have made direct comparison of results difficult. In fact, some authors have called for increasing standardization of reporting among the stroke community using angiographic reperfusion to enhance generalizability.14 , 15 In this paper we review the current grading systems for recanalization/reperfusion, discuss the current controversies in grading systems and the need for standardization of recanalization and reperfusion in trial reporting. Finally, we offer a revised grading system that accounts for less than perfect but clearly excellent reperfusion within its scale.Keywords
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