Cyclic AMP-dependent Protein Kinase Signaling Modulates Pregnane x Receptor Activity in a Species-specific Manner
Open Access
- 1 March 2009
- journal article
- Published by Elsevier BV in Journal of Biological Chemistry
- Vol. 284 (11), 6639-6649
- https://doi.org/10.1074/jbc.m807426200
Abstract
No abstract availableKeywords
This publication has 37 references indexed in Scilit:
- Cyclin-dependent Kinase 2 Negatively Regulates Human Pregnane X Receptor-mediated CYP3A4 Gene Expression in HepG2 Liver Carcinoma CellsJournal of Biological Chemistry, 2008
- A novel panel of mouse models to evaluate the role of human pregnane X receptor and constitutive androstane receptor in drug responseJCI Insight, 2008
- The Traditional Chinese Herbal Remedy Tian Xian Activates Pregnane X Receptor and Induces CYP3A Gene Expression in HepatocytesPublished by American Society for Pharmacology & Experimental Therapeutics (ASPET) ,2008
- Cell Signaling and Nuclear Receptors: New Opportunities for Molecular Pharmaceuticals in Liver DiseaseMolecular Pharmaceutics, 2007
- Human nuclear pregnane X receptor cross-talk with CREB to repress cAMP activation of the glucose-6-phosphatase geneBiochemical Journal, 2007
- Nuclear Pregnane X Receptor Cross-talk with FoxA2 to Mediate Drug-induced Regulation of Lipid Metabolism in Fasting Mouse LiverJournal of Biological Chemistry, 2007
- The role of intracellular signaling in insulin-mediated regulation of drug metabolizing enzyme gene and protein expressionPharmacology & Therapeutics, 2007
- The Pregnane X Receptor Gene-Humanized Mouse: A Model for Investigating Drug-Drug Interactions Mediated by Cytochromes P450 3APublished by American Society for Pharmacology & Experimental Therapeutics (ASPET) ,2006
- Regulation of Constitutive Androstane Receptor and Its Target Genes by Fasting, cAMP, Hepatocyte Nuclear Factor α, and the Coactivator Peroxisome Proliferator-activated Receptor γ Coactivator-1αPublished by Elsevier BV ,2006
- Mutual repression between steroid and xenobiotic receptor and NF- B signaling pathways links xenobiotic metabolism and inflammationJCI Insight, 2006