Motor Neuron Transduction After Intracisternal Delivery of AAV9 in a Cynomolgus Macaque
- 1 April 2015
- journal article
- research article
- Published by Mary Ann Liebert Inc in Human Gene Therapy Methods
- Vol. 26 (2), 43-44
- https://doi.org/10.1089/hgtb.2015.041
Abstract
The image shows a section of the lumbar spinal cord from a cynomolgus macaque that had received AAV9.CB.EGFP via the cisterna magna. Expression of GFP in multiple motor neurons is visible. Injection into the cerebrospinal fluid has been shown to be an effective route of vector administration for neuron transduction.Keywords
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