Nanoparticles: small and mighty
- 23 February 2011
- journal article
- review article
- Published by Wiley in International Journal of Dermatology
- Vol. 50 (3), 247-254
- https://doi.org/10.1111/j.1365-4632.2010.04815.x
Abstract
The properties of engineered nanomaterials and nanoparticles such as zinc oxide and titanium dioxide may differ substantially from naturally occurring materials and particles. Nanoparticles have unique physical properties making them ideal for use in various skin care products currently on the market. Nano-preparations are currently under investigation as novel treatments of acne vulgaris, recurrent condyloma accuminata, atopic dermatitis, hyperpigmented skin lesions, and other non-dermatologic diseases. Because of their increased surface area, nanoparticles have increased reactivity and a small size allowing for enhanced mobility through the human body and environment. As their use becomes more prevalent, nanoparticles are being scrutinized for their safety and long-term effects. This review discusses the benefits of nanoparticles in dermatological therapies and skin care products as well as potential disadvantages and possible mechanisms of toxicity.Keywords
This publication has 37 references indexed in Scilit:
- The use of biotinylated-EGF-modified gelatin nanoparticle carrier to enhance cisplatin accumulation in cancerous lungs via inhalationBiomaterials, 2009
- Nanoparticle–chelator conjugates as inhibitors of amyloid-β aggregation and neurotoxicity: A novel therapeutic approach for Alzheimer diseaseNeuroscience Letters, 2009
- Formulation of Nanoparticle-Eluting Stents by a Cationic Electrodeposition Coating Technology: Efficient Nano-Drug Delivery via Bioabsorbable Polymeric Nanoparticle-Eluting Stents in Porcine Coronary ArteriesJACC: Cardiovascular Interventions, 2009
- Patents and nanomedicineNanomedicine, 2007
- Grey Gooon the Skin? Nanotechnology, Cosmetic and Sunscreen SafetyCritical Reviews in Toxicology, 2007
- Antibiotic-conjugated polyacrylate nanoparticles: New opportunities for development of anti-MRSA agentsBioorganic & Medicinal Chemistry Letters, 2007
- Nano-titanium dioxide composites for the enrichment of phosphopeptidesJournal of Chromatography A, 2006
- Environmentally Responsible Development of NanotechnologyEnvironmental Science & Technology, 2005
- Microstructural Characterization of a Fumed Titanium Dioxide PhotocatalystJournal of Solid State Chemistry, 1995
- Clinical pharmacokinetics of doxorubicin in hepatoma patients after a single intravenous injection of free or nanoparticle-bound anthracyclineInternational Journal of Pharmaceutics, 1989