METASTASES OF THE BONE IN PRIMARY CARCINOMA OF THE LUNG

Abstract

Some phases of the study of malignant tumors have been more actively prosecuted during recent years than others; for example, the experimental production of tumors in animals with tar and allied substances, the influence of heredity and of racial susceptibility and the statistics of tumor incidence. Malignant tumors of the bones and primary carcinomas of the lungs have also received a large amount of attention. The opportunity to secure complete postmortem examinations of the bodies of four patients, who died with primary tumors of the lungs and secondary growths in one or more bones, has led to a review of the literature and to some suggestions which, it is hoped, may be useful. We are indebted to Dr. George Dick for permission to include an account of the clinical features of the illness of the first of these patients, and to Dr. Carl Apfelbach for his record of the postmortem