Crystal structures of mutant monomeric hexokinase I reveal multiple ADP binding sites and conformational changes relevant to allosteric regulation
- 3 March 2000
- journal article
- Published by Elsevier BV in Journal of Molecular Biology
- Vol. 296 (4), 1001-1015
- https://doi.org/10.1006/jmbi.1999.3494
Abstract
No abstract availableKeywords
This publication has 54 references indexed in Scilit:
- Nonaggregating Mutant of Recombinant Human Hexokinase I Exhibits Wild-Type Kinetics and Rod-like Conformations in SolutionBiochemistry, 1999
- Regulation of hexokinase I: crystal structure of recombinant human brain hexokinase complexed with glucose and phosphateJournal of Molecular Biology, 1998
- Refinement of Macromolecular Structures by the Maximum-Likelihood MethodActa crystallographica. Section D, Structural biology, 1997
- Complexes between kinases, mitochondrial porin and adenylate translocator in rat brain resemble the permeability transition poreFEBS Letters, 1996
- The CCP4 suite: programs for protein crystallographyActa crystallographica. Section D, Structural biology, 1994
- A visual protein crystallographic software system for X11/XviewJournal of Molecular Graphics, 1992
- Inhibition of brain hexokinase by a multisubstrate analog results from binding to a discrete regulatory siteBiochemical and Biophysical Research Communications, 1984
- Structure of a complex between yeast hexokinase A and glucose: II. Detailed comparisons of conformation and active site configuration with the native hexokinase B monomer and dimerJournal of Molecular Biology, 1980
- A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye bindingAnalytical Biochemistry, 1976
- Purification and properties of rat skeletal muscle hexokinaseFEBS Letters, 1976