RETRACTED: Major essential oils composition and immunotoxicity activity from leaves ofFoeniculum vulgareagainstAedes aegyptiL
- 29 July 2010
- journal article
- retracted article
- Published by Taylor & Francis Ltd in Immunopharmacology and Immunotoxicology
- Vol. 33 (3), 450-453
- https://doi.org/10.3109/08923973.2010.532805
Abstract
The leaves of Foeniculum vulgare (Umbelliferae) were extracted and the major essential oil composition and immunotoxicity effects were studied. The analyses conducted by gas chromatography and mass spectroscopy (GC-MS) revealed the essential oils of F. vulgare leaves. The F. vulgare essential oil yield was 0.97%, and GC/MS analysis revealed that its major constituents were methyl clavicol (46.3%), α-phellandrene (18.2%), fenchone (10.6%), (E)-anethole (11.3%), myrcene (3.4%), and α-pinene (2.1%). The essential oil had a significant toxic effect against early fourth-stage larvae of Aedes aegypti L with an LC(50) value of 41.23 ppm and an LC(90) value of 65.24 ppm. Also, methyl clavicol (≥98.0%), α-phellandrene (≥95.0%), fenchone (≥98.0%), (E)-anethole (≥99.0%), myrcene (≥99.0%), and α-pinene (≥99.0%) were tested against the F(21) laboratory strain of A. aegypti. Fenchone (≥98.0%) and (E)-anethole (≥99.0%) have medium activity with an LC(50) value of 73.11 ppm and 102.41 ppm. The above data indicate that major compounds interaction may play a more important role in the toxicity of essential oil.Keywords
This publication has 13 references indexed in Scilit:
- Antioxidant and antimicrobial activities of essential oil and extracts of fennel (Foeniculum vulgare Mill.) seeds from PakistanFlavour and Fragrance Journal, 2009
- Chemical constituents and larvicidal property of the essential oil of Blumea mollis (D. Don) Merr. against Culex quinquefasciatusZeitschrift für Parasitenkunde, 2008
- Larvicidal activity of essential oils extracted from commonly used herbs in Lebanon against the seaside mosquito, Ochlerotatus caspiusBioresource Technology, 2008
- Aromatic plant-derived essential oil: An alternative larvicide for mosquito controlFitoterapia, 2007
- Comparative Chemical Composition and Antioxidant Activities of Wild and Cultivated Laurus nobilis L. Leaves and Foeniculum vulgare subsp. piperitum (Ucria) Coutinho SeedsBiological & Pharmaceutical Bulletin, 2006
- Bioactivity of selected plant essential oils against the yellow fever mosquito Aedes aegypti larvaeBioresource Technology, 2003
- Comparison of essential oil composition of Iranian fennel (Foeniculum vulgare) obtained by supercritical carbon dioxide extraction and hydrodistillation methodsFlavour and Fragrance Journal, 2002
- Phytochemical and chemotaxonomic studies of Foeniculum vulgareBiochemical Systematics and Ecology, 1997
- Blood-Feeding Patterns of Aedes aegypti (Diptera: Culicidae) Collected in a Rural Thai VillageJournal of Medical Entomology, 1993
- The Influence of Distillation Conditions on the Essential Oil Composition of Three Varieties ofFoeniculum vulgareMill.Journal of Essential Oil Research, 1992