Arguing against the proposed definition changes of PD
Open Access
- 5 August 2016
- journal article
- editorial
- Published by Wiley in Movement Disorders
- Vol. 31 (11), 1619-1622
- https://doi.org/10.1002/mds.26721
Abstract
As members of the Lewy Body Dementia Association Scientific Advisory Council, we aim to address some of the issues raised in the article titled “Time to Redefine PD? Introductory Statement of the MDS Task Force on the Definition of Parkinson's Disease.” In particular, we suggest that the 1‐year rule distinguishing Parkinson's disease dementia from dementia with Lewy bodies is worth maintaining because it serves an important purpose in clinical practice and clinical and basic science research and when helping the lay community understand the complexity of these different clinical phenotypes. Furthermore, we believe that adding an additional diagnostic label, “PD (dementia with Lewy bodies subtype),” will confuse rather than clarify the distinction between dementia with Lewy bodies and PD or PD dementia, and will not improve management or expedite therapeutic development. We present arguments supporting our contentions. © 2016 The Authors. Movement Disorders published by Wiley Periodicals, Inc. on behalf of International Parkinson and Movement Disorder Society.Keywords
This publication has 24 references indexed in Scilit:
- Imaging the Role of Amyloid in PD Dementia and Dementia with Lewy BodiesCurrent Neurology and Neuroscience Reports, 2014
- The Mild Cognitive Impairment Stage of Dementia With Lewy Bodies and Parkinson DiseaseAlzheimer Disease & Associated Disorders, 2014
- Time to redefine PD? Introductory statement of the MDS Task Force on the definition of Parkinson's diseaseMovement Disorders, 2014
- Nonamnestic mild cognitive impairment progresses to dementia with Lewy bodiesNeurology, 2013
- Association of a polymorphism in mitochondrial transcription factor A (TFAM) with Parkinson's disease dementia but not dementia with Lewy bodiesNeuroscience Letters, 2013
- Clinicopathologic correlations in 172 cases of rapid eye movement sleep behavior disorder with or without a coexisting neurologic disorderSleep Medicine, 2013
- APOE ϵ4 Increases Risk for Dementia in Pure SynucleinopathiesJAMA Neurology, 2013
- Inclusion of RBD improves the diagnostic classification of dementia with Lewy bodiesNeurology, 2011
- Amyloid load in Parkinson's disease dementia and Lewy body dementia measured with [11C]PIB positron emission tomographyJournal of Neurology, Neurosurgery & Psychiatry, 2008
- Verbal and visuospatial deficits in dementia with Lewy bodiesNeurology, 2005