Licking latency with licorice
- 1 March 2005
- journal article
- editorial
- Published by American Society for Clinical Investigation in JCI Insight
- Vol. 115 (3), 591-593
- https://doi.org/10.1172/jci24507
Abstract
Numerous viruses cause latent infections in humans, and reactivation often results in pain and suffering. While vaccines for several of these viruses are available or currently being studied in clinical trials, and antiviral therapies have been successful in preventing or treating active infection, therapy to eradicate latent infection has lagged behind. A new study reported in this issue of the JCI shows that treatment of cells latently infected with Kaposi sarcoma–associated herpesvirus (KSHV) with glycyrrhizic acid, a component of licorice, reduces synthesis of a viral latency protein and induces apoptosis of infected cells. This finding suggests a novel way to interrupt latency.This publication has 23 references indexed in Scilit:
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