A efetividade do dentifrício fluoretado no controle da cárie dental: uma meta-análise
Open Access
- 1 October 2002
- journal article
- abstracts
- Published by FapUNIFESP (SciELO) in Revista de Saúde Pública
- Vol. 36 (5), 598-606
- https://doi.org/10.1590/s0034-89102002000600009
Abstract
To carry out a meta-analysis on the effectiveness of fluoride toothpaste for reducing dental caries to calculate the effect size of different hypothesis. MEDLINE and LILACS databases were studied in the period from 1980 to 1998. To evaluate the quality of the studies, methodological rigor criteria proposed by Kay & Locker (1996) were applied after the criteria were submitted to an expert committee of CNPq (National Scientific Council of Brazil) senior researchers. Of 43 papers selected, 22 met the proposed criteria. The effect size of intervention was calculated from differences among the groups and the overall effect of five groups of hypothesis. The high concentration of fluoride in the toothpaste is associated with a larger effect (overall effect = -0.17 CI 95% -0.22/-0.12). The largest caries reductions were observed when comparing fluoride toothpastes and no fluoride toothpastes (overall effect = -0.29 IC 95% -0.34/-0.24). The addiction of antimicrobial agents (overall effect = -0.03 IC 95% -0.07/+0.02), differences in abrasive systems (overall effect = -0.02 IC 95% -0.09/+0.04) and active components do not increase the effectiveness of fluoride toothpastes (overall effect = -0.04 IC 95% -0.10/+0.01). The highest caries reductions were seen in studies where there was supervised tooth brushing. This review reinforced the importance of tooth brushing with fluoride toothpastes for controlling dental caries. However it showed the emphasis put on medical approaches for disease control rather than specific educational actions. The heterogeneity of the results shows the need to consider issues such as the scenario for implementing preventive methods in the evaluation process.This publication has 20 references indexed in Scilit:
- Comparative Three-Year Caries Protection from an Aluminium-Containing and a Fluoride-Containing ToothpasteCaries Research, 1997
- Direct Evidence Concerning the ‘Major Role’ of Fluoride Dentifrices in the Caries Decline: A 6-year Analytical Cohort StudyActa Odontologica Scandinavica, 1997
- Is dental health education effective? A systematic review of current evidenceCommunity Dentistry and Oral Epidemiology, 1996
- Reasons for the caries decline: what do the experts believe?European Journal of Oral Sciences, 1996
- A 30-Month Study Investigating the Effect of Adding Triclosan/ Copolymer to a Fluoride DentifriceCaries Research, 1995
- Comparative Efficacy of NaF and SMFP Dentifrices in Caries Prevention: A Meta-Analytic OverviewCaries Research, 1993
- Caries-Preventive Effect of Fluoride Dentifrices with and without Anticalculus Agents: A 3-Year Controlled Clinical TrialCaries Research, 1990
- A 3-year clinical trial to compare efficacy of dentifrices containing 1.14% and 0.76% sodium monofluorophosphateCommunity Dentistry and Oral Epidemiology, 1988
- Criteria and Standards for Quality Assessment and MonitoringQRB - Quality Review Bulletin, 1986
- A Four-Year Clinical Study to Determine the Caries-Inhibiting Effect of Calcium Glycerophosphate and Sodium Fluoride in Calcium Carbonate Base Dentifrices Containing Sodium MonofluorophosphateCaries Research, 1983