Prenatal and Perinatal Risk Factors for Autism in China
Open Access
- 1 April 2010
- journal article
- research article
- Published by Springer Science and Business Media LLC in Journal of Autism and Developmental Disorders
- Vol. 40 (11), 1311-1321
- https://doi.org/10.1007/s10803-010-0992-0
Abstract
We conducted a case–control study using 190 Han children with and without autism to investigate prenatal and perinatal risk factors for autism in China. Cases were recruited through public special education schools and controls from regular public schools in the same region (Tianjin), with frequency matching on sex and birth year. Unadjusted analyses identified seven prenatal and seven perinatal risk factors significantly associated with autism. In the adjusted analysis, nine risk factors showed significant association with autism: maternal second-hand smoke exposure, maternal chronic or acute medical conditions unrelated to pregnancy, maternal unhappy emotional state, gestational complications, edema, abnormal gestational age (42 weeks), nuchal cord, gravidity >1, and advanced paternal age at delivery (>30 year-old).Keywords
This publication has 68 references indexed in Scilit:
- Independent and dependent contributions of advanced maternal and paternal ages to autism riskAutism Research, 2010
- Activation of the maternal immune system alters cerebellar development in the offspringBrain, Behavior, and Immunity, 2009
- Prenatal stress and risk for autismNeuroscience & Biobehavioral Reviews, 2008
- Advanced Parental Age and the Risk of Autism Spectrum DisorderAmerican Journal of Epidemiology, 2008
- Neonatal jaundice: a risk factor for infantile autism?Paediatric and Perinatal Epidemiology, 2008
- Advanced Parental Age at Birth Is Associated With Poorer Social Functioning in Adolescent Males: Shedding Light on a Core Symptom of Schizophrenia and AutismSchizophrenia Bulletin, 2008
- Perinatal risk factors and infantile autismActa Psychiatrica Scandinavica, 2006
- Estimation of Direct Causal EffectsEpidemiology, 2006
- Prenatal Infection as a Risk Factor for SchizophreniaSchizophrenia Bulletin, 2006
- PRE‐. PERI‐, AND NEONATAL FACTORS AND INFANTILE AUTISMJournal of Child Psychology and Psychiatry, 1979