DoGSiteScorer: a web server for automatic binding site prediction, analysis and druggability assessment
Top Cited Papers
Open Access
- 23 May 2012
- journal article
- research article
- Published by Oxford University Press (OUP) in Bioinformatics
- Vol. 28 (15), 2074-2075
- https://doi.org/10.1093/bioinformatics/bts310
Abstract
Motivation: Many drug discovery projects fail because the underlying target is finally found to be undruggable. Progress in structure elucidation of proteins now opens up a route to automatic structure-based target assessment. DoGSiteScorer is a newly developed automatic tool combining pocket prediction, characterization and druggability estimation and is now available through a web server. Availability: The DoGSiteScorer web server is freely available for academic use at http://dogsite.zbh.uni-hamburg.de Contact:rarey@zbh.uni-hamburg.de.Keywords
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