An Apparently New Lethal Virus Disease of Infant Mice
- 27 July 1962
- journal article
- research article
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 137 (3526), 282-283
- https://doi.org/10.1126/science.137.3526.282
Abstract
A hitherto unreported disease of infant mice is described. The agent reproduces upon passage, is filterable, is confined mainly to the gastrointestinal tract in infant and adult mice, causes death in infants and inapparent infection in adults, and is sensitive to mild heat, ether, and sodium deoxycholate. Unique and characteristic morphologic changes occur in the epithelial cells of the intestine in infected infant mice. These consist in the development of multinucleated giant cells designated "balloon cells.".Keywords
This publication has 2 references indexed in Scilit:
- STUDIES ON THE ETIOLOGY AND TRANSMISSION OF EPIDEMIC DIARRHEA OF INFANT MICEThe Journal of Experimental Medicine, 1957
- EPIDEMIC DIARRHEAL DISEASE OF SUCKLING MICEAnnals of the New York Academy of Sciences, 1956