Epidemiological evidence for causal relationship between Epstein-Barr virus and Burkitt's lymphoma from Ugandan prospective study
- 24 August 1978
- journal article
- research article
- Published by Springer Science and Business Media LLC in Nature
- Vol. 274 (5673), 756-761
- https://doi.org/10.1038/274756a0
Abstract
Results from a prospective sero-epidemiological study initiated in Uganda in 1971 indicate that children with high antibody titres to Epstein-Barr virus structural antigens are at high risk of developing Burkitt's lymphoma. These findings strongly support a causal relationship between the Epstein-Barr virus and Burkitt's lymphoma but suggest that the oncogenic potential of the virus is realised only in exceptional circumstances.Keywords
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