Interstitial pneumonitis associated with infliximab therapy without methotrexate treatment
- 17 April 2009
- journal article
- case report
- Published by Springer Science and Business Media LLC in Rheumatology International
- Vol. 30 (2), 275-276
- https://doi.org/10.1007/s00296-009-0931-6
Abstract
Tumor necrosis factor (TNF)-α inhibitors are increasingly being used to treat rheumatoid arthritis. Infliximab (INF) is a TNF-α inhibitor that is usually used in combination with methotrexate (MTX). Interstitial lung disease (ILD) during combination therapy has been attributed to MTX rather than INF. However, INF-associated ILD without combination with MTX has recently been reported. We describe herein a case of severe ILD secondary to INF without MTX therapy.Keywords
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