Systolic and diastolic left ventricular dysfunction: from risk factors to overt heart failure
- 1 February 2010
- journal article
- review article
- Published by Informa UK Limited in Expert Review of Cardiovascular Therapy
- Vol. 8 (2), 251-258
- https://doi.org/10.1586/erc.10.3
Abstract
Because life expectancy and the prevalence of risk factors such as hypertension, obesity and diabetes are rising globally, heart failure (HF) is growing into a major health problem. Impairment of left ventricular (LV) diastolic function as well as systolic function appear very early in the course of heart disease. Recent HF guidelines, therefore, place special emphasis on the detection of subclinical LV dysfunction and the timely identification of risk factors for HF. Conventional echocardiography combined with new imaging techniques such as tissue Doppler and tissue tracking are sensitive tools to detect early subclinical deterioration of LV function. Community-based studies revealed a higher prevalence of LV systolic and diastolic dysfunction using the new echocardiographic imaging techniques. Future prospective studies will clarify the hitherto unknown prognosis associated with early symptom-free LV dysfunction.Keywords
This publication has 32 references indexed in Scilit:
- Cardiac Dysfunction Assessed by Echocardiographic Tissue Doppler Imaging Is an Independent Predictor of Mortality in the General PopulationCirculation, 2009
- Prevalence of Left Ventricular Diastolic Dysfunction in a General PopulationCirculation: Heart Failure, 2009
- Left ventricular strain and strain rate in a general populationEuropean Heart Journal, 2008
- Ejection fraction: a measure of desperation?Heart, 2007
- Prevalence and Prognostic Significance of Heart Failure StagesCirculation, 2007
- Left Atrial SizeJournal of the American College of Cardiology, 2006
- Incremental predictive power of B-type natriuretic peptide and tissue Doppler echocardiography in the prognosis of patients with congestive heart failureJournal of the American College of Cardiology, 2005
- Mitral flow derived Doppler indices of left ventricular diastolic function in a general population. The Tromsø studyPublished by Oxford University Press (OUP) ,2000
- Left ventricular contraction pattern changes with age in normal adultsJournal of the American Society of Echocardiography, 1998
- Changes in Nonmyocyte Tissue Composition Associated with Pressure Overload of Hypertrophic Human HeartsPathology - Research and Practice, 1989