Cefazolin vs Moxalactam? A Double-blind Randomized Trial of Cephalosporins in Head and Neck Surgery
- 1 February 1986
- journal article
- clinical trial
- Published by American Medical Association (AMA) in JAMA Otolaryngology–Head & Neck Surgery
- Vol. 112 (2), 151-153
- https://doi.org/10.1001/archotol.1986.03780020031008
Abstract
• Cefazolin and moxalactam were compared in a prospective randomized double-blind trial of 118 patients undergoing oncologic head and neck surgery. Both antibiotics were given 2 g every four hours for four doses. Five infections were encountered in the cefazolin group (8.5%) and two infections in the moxalactam group (3.4%); this difference was not statistically significant. This assessment does not indicate, however, that the two regimens are equally efficacious. (Arch Otolaryngol Head Neck Surg1986;112:151-153)Keywords
This publication has 6 references indexed in Scilit:
- Cost‐Effectiveness of Prophylactic Antibiotics in Head and Neck SurgeryOtolaryngology -- Head and Neck Surgery, 1984
- Third-Generation and Investigational Cephalosporins: II. Microbiologic Review and Clinical SummariesDrug Intelligence & Clinical Pharmacy, 1983
- Cefoperazone as a Prophylactic Agent in Abdominal HysterectomyClinical Infectious Diseases, 1983
- Comparative study of cefazolin, cefoxitin, and ceftizoxime for surgical prophylaxis in colo-rectal surgeryJournal of Antimicrobial Chemotherapy, 1982
- Cefazolin Prophylaxis in Head and Neck Cancer SurgeryAnnals of Otology, Rhinology & Laryngology, 1979
- PROPHYLACTIC ANTIBIOTICS IN PENETRATING WOUNDS OF THE ABDOMENThe Journal of Trauma and Acute Care Surgery, 1972