Review of Pharmacological Effects ofAntrodia camphorataand Its Bioactive Compounds
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Open Access
- 1 January 2011
- journal article
- review article
- Published by Hindawi Limited in Evidence-Based Complementary and Alternative Medicine
- Vol. 2011, 1-17
- https://doi.org/10.1093/ecam/nep108
Abstract
Antrodia camphorata is a unique mushroom of Taiwan, which has been used as a traditional medicine for protection of diverse health-related conditions. In an effort to translate this Eastern medicine into Western-accepted therapy, a great deal of work has been carried out on A. camphorata. This review discusses the biological activities of the crude extracts and the main bioactive compounds of A. camphorata. The list of bioactivities of crude extracts is huge, ranging from anti-cancer to vasorelaxation and others. Over 78 compounds consisting of terpenoids, benzenoids, lignans, benzoquinone derivatives, succinic and maleic derivatives, in addition to polysaccharides have been identified. Many of these compounds were evaluated for biological activity. Many activities of crude extracts and pure compounds of A. camphorata against some major diseases of our time, and thus, a current review is of great importance. It is concluded that A. camphorata can be considered as an efficient alternative phytotherapeutic agent or a synergizer in the treatment of cancer and other immune-related diseases. However, clinical trails of human on A. camphorata extracts are limited and those of pure compounds are absent. The next step is to produce some medicines from A. camphorata, however, the production may be hampered by problems related to mass production.Keywords
Funding Information
- Ministry of Education, Taiwan
This publication has 87 references indexed in Scilit:
- Inhibition of Anchorage-Independent Proliferation and G0/G1 Cell-Cycle Regulation in Human Colorectal Carcinoma Cells by 4,7-Dimethoxy-5-Methyl-l,3-Benzodioxole Isolated from the Fruiting Body ofAntrodia camphorateEvidence-Based Complementary and Alternative Medicine, 2011
- An Extract ofAntrodia camphorataMycelia Attenuates the Progression of Nephritis in Systemic Lupus Erythematosus-Prone NZB/W F1 MiceEvidence-Based Complementary and Alternative Medicine, 2011
- Characterization and biological functions of sulfated polysaccharides from sulfated-salt treatment of Antrodia cinnamomeaProcess Biochemistry, 2009
- Effect of culture pH on the antioxidant properties of Antrodia camphorata in submerged cultureJournal of the Chinese Institute of Chemical Engineers, 2008
- Phylogenetic analysis of Antrodia species and Antrodia camphorata inferred from internal transcribed spacer regionAntonie van Leeuwenhoek, 2006
- Adenosine as an active component of Antrodia cinnamomea that prevents rat PC12 cells from serum deprivation-induced apoptosis through the activation of adenosine A2A receptorsLife Sciences, 2006
- Regulatory T Cells, a Potent Immunoregulatory Target for CAM Researchers: Modulating Tumor Immunity, Autoimmunity and Alloreactive Immunity (III)Evidence-Based Complementary and Alternative Medicine, 2006
- Study for anti-angiogenic activities of polysaccharides isolated from Antrodia cinnamomea in endothelial cellsLife Sciences, 2005
- Characterization and Functional Study of Antrodia camphorata LipopolysaccharideJournal of Agricultural and Food Chemistry, 2004
- Antrodia cinnamomea sp. nov. on Cinnamomum kanehirai in TaiwanMycological Research, 1995