Disc replacement using Pro-Disc C versus fusion: a prospective randomised and controlled radiographic and clinical study
- 14 November 2006
- journal article
- research article
- Published by Springer Science and Business Media LLC in European Spine Journal
- Vol. 16 (3), 423-430
- https://doi.org/10.1007/s00586-006-0226-5
Abstract
Anterior cervical discectomy and fusion (ACDF) may be considered to be the gold standard for treatment of symptomatic degenerative disc disease within the cervical spine. However, fusion of the segment may result in progressive degeneration of the adjacent segments. Therefore, dynamic stabilization procedures have been introduced. Among these, artificial disc replacement by disc prosthesis seems to be promising. However, to be so, segmental motion must be preserved. This, again, is very difficult to judge and has not yet been proven. The aim of the current study was to first analyse the segmental motion following artificial disc replacement using a disc prosthesis. A second aim was to compare both segmental motion as well as clinical result to the current gold standard (ACDF). This is a prospective controlled study. Twenty-five patients with cervical disc herniation were enrolled and assigned to either study group (receiving a disc prosthesis) or control group (receiving ACDF, using a cage with bone graft and an anterior plate.) Radiostereometric analysis was used to quantify intervertebral motion immediately as well as 3, 6, 12 and 24 weeks postoperatively. Further, clinical results were judged using visual analogue scale and neuro-examination. Cervical spine segmental motion decreased over time in the presence of disc prosthesis or ACDF. However, the loss of segmental motion is significantly higher in the ACDF group, when looked at 3, 6, 12 and 24 weeks after surgery. We observed significant pain reduction in neck and arm postoperatively, without significant difference between both groups (P > 0.05). Cervical spine disc prosthesis preserves cervical spine segmental motion within the first 6 months after surgery. The clinical results are the same when compared to the early results following ACDF.Keywords
This publication has 49 references indexed in Scilit:
- Early results after ProDisc-C cervical disc replacementJournal of Neurosurgery: Spine, 2005
- Cervical arthroplasty complicated by delayed spontaneous fusionJournal of Neurosurgery: Spine, 2005
- Choosing a cervical disc replacementThe Spine Journal, 2004
- Primary Lumbosacral Stability After Open Posterior and Endoscopic Anterior Fusion With Interbody ImplantsSpine, 2000
- Anterior Discectomy and Fusion for Painful Cervical Disc DiseaseSpine, 1998
- Plate fixation adds stability to two-level anterior fusion in the cervical spine: a randomized study using radiostereometryEuropean Spine Journal, 1998
- A comparison of pain measurement characteristics of mechanical visual analogue and simple numerical rating scalesPain, 1994
- The accuracy of measurements of femoral neck fracturesActa Orthopaedica, 1992
- Mobility of the lateral malleolus: A roentgen stereophotogrammetric analysisActa Orthopaedica, 1985
- Studies with pain rating scales.Annals Of The Rheumatic Diseases, 1978