Sublethal Effects of Monocrotophos on Locomotor Behavior and Gill Architecture of the Mosquito Fish,Gambusia affinis
- 1 November 2005
- journal article
- research article
- Published by Taylor & Francis Ltd in Journal of Environmental Science and Health, Part B
- Vol. 40 (6), 813-825
- https://doi.org/10.1080/03601230500227509
Abstract
Subacute studies of monocrotophos [Dimethyl (E)-1-methyl-2-(methyl-carbamoyl) vinyl phosphate] on mosquito fish, Gambusia affinis, were carried out in vivo for 24 days to assess the locomotor behavior, structural integrity of gill, and targeted enzyme acetylcholinesterase (AChE, EC: 3.1.1.7) interactions. Monocrotophos (MCP) can be rated as moderately toxic to G. affinis, with a median lethal concentration (LC50) of 20.49 ± 2.45 mgL−1. The fish exposed to sublethal concentration of LC10 (7.74 mgL−1) were under stress and altered their locomotor behavior, such as distance traveled per unit time (m min−1) and swimming speed (cm sec−1) with respect to the length of exposure. Inhibition in the activity of brain AChE and deformities in the primary and secondary lamellae of gill may have resulted in failure of exchange of gases. The maximum inhibition of 95% of AChE activity was observed on days 20 and 24. Morphological aberrations in the gills were also studied during exposure to the sublethal concentration of monocrotophos for a period ranging from 8 to 24 days. The extent of damage in gill was dependent on the duration of exposure. The findings revealed that inhibition in brain AChE activity and structural alteration in gill were responsible for altering the locomotor behavior of exposed fish.Keywords
This publication has 25 references indexed in Scilit:
- A portrait of locomotor behaviour in Drosophila determined by a video-tracking paradigmBehavioural Processes, 2004
- Effects of the organophosphorous methyl parathion on the branchial epithelium of a freshwater fish Metynnis rooseveltiBrazilian Archives of Biology and Technology, 2003
- Effects of Diazinon on bluegill sunfish, Lepomis macrochirus, gills: scanning electron microscope observationsExperimental Biology Online, 1997
- Effects of exposure to an organophosphate pesticide on behavior and acetylcholinesterase activity in the common shrew, Sorex araneusEnvironmental Toxicology and Chemistry, 1997
- ASSESSMENT OF MOTOR ACTIVITY IN REGULATORY NEUROTOXICITY STUDIES: VALIDATION OF THE ETHOVISION VIDEO TRACKING SYSTEM IN RATS TREATED WITH AMPHETAMINE AND CHLORPROMAZINEToxicology Mechanisms and Methods, 1997
- Ultrastructural changes in the respiratory lamellae of the catfish, Heteropneustes fossilis after sublethal exposure to malathionEnvironmental Pollution, 1996
- Ethological and experimental approaches to behavior analysis: implications for ecotoxicology.Environmental Health Perspectives, 1996
- In vitro brain acetylcholinesterase response among three inbred strains of mice to monocrotophosJournal of Environmental Science and Health, Part B, 1991
- In Vitro inhibition of acetylcholinesterase from four marine species by organophosphates and carbamatesBulletin of Environmental Contamination and Toxicology, 1990
- Histopathological changes induced by malathion in the gills of bluegillLepomis macrochirusBulletin of Environmental Contamination and Toxicology, 1989