Olfactory Bulb Volume in Taiwanese Patients with Posttraumatic Anosmia
- 1 November 2009
- journal article
- research article
- Published by SAGE Publications in American Journal of Rhinology and Allergy
- Vol. 23 (6), 582-584
- https://doi.org/10.2500/ajra.2009.23.3370
Abstract
Background: Olfactory bulb (OB) volume has been shown to be an indicator of olfactory function. However, few studies have been done in Asia to investigate the influence of different disorders on OB volume. Methods: Data from patients with posttraumatic anosmia were collected in our department. Their olfactory thresholds were assessed by the phenyl ethyl alcohol threshold test. They were treated with a course of high-dose steroid, and followed up for at least 3 months without any olfactory improvement. Magnetic resonance imaging was subsequently used to measure patients’ OB volumes. Subjects who self-reported their olfactory function was normal were also included in the control group for comparison. Results: Fifty-four patients with posttraumatic anosmia and 30 subjects who self-reported their olfactory function was normal were enrolled in this study. The mean right OB volume was 45.2 mm3, and the mean left OB volume was 46.3 mm3 in patients with posttraumatic anosmia. The mean right OB volume was 59.7 mm3, and the mean left OB volume was 66.0 mm3 in control subjects. The OB volumes were significantly lower in patients with posttraumatic anosmia. Conclusion: OB volumes were significantly lower in Taiwanese patients with posttraumatic anosmia.Keywords
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